Dating to the 3rd century AD, this manuscript is one of the oldest surviving substantial copies of the Book of Genesis in Greek. It contains portions of sixteen chapters, providing an important early look at how the Scriptures were read and copied by early Christian communities.

Codex Alexandrinus is one of the four great uncial codices of the Greek Bible. It contains the vast majority of the Septuagint and New Testament, and was the first of the great uncials to become accessible to modern scholars.